This area is frequented by some very dangerous and aggressive creatures, many of which are similar to other areas of the Plains of Karana (hill giants, griffawns) and many more which are unique to this area (the gnoll and undead reavers, gorge hounds and war wolves, evil eyes, lion and lioness royalty). There is a lot of good hunting here, but it comes at the price of being very dangerous.

Given that this is the case, there are few places to hunt safely(other than the edges of the zone) and no real guard to protect you or to run to. Random death is the key here, and with so many creatures running around who are aggressive (it's like you're in an angry zoo) I wouldn't recommend hunting here until you reach 15th level, unless you are very good at avoiding dangers.

Also note the presence of very high level killing machines that are here, like the evil eyes, Broon and cyclops, name gnolls. Even if you're hunting carefully within your level, these can certainly spoil your day.

This area provides good hunting from 15th until about 25th level, roughly, as the area is just jam-packed with monsters that you'll be able to hunt. It also is somewhat less crowded than areas that are closer to the main cities. This makes the area good hunting for a careful group.

Many a crag spiders spawn here, which can drop up to 10 spider silks at one time, making this a great farming location. A popular hunting place for these spiders are around location #6 on the map.

The Haunted Obelisk is a good place to camp a gnoll reaver and at night an undead reaver. The gnolls are spread apart, making them easy to kite. They can be kited back to the shore of the river, where enemies do not spawn or patrol.

Sir Morgan is a well-known feature of this area. He is a plate-clad knight who hangs out just east of the bridge from Northern Karana with his squire and offers to guide you to the other side and protect you along the way. His price is fairly cheap, and if you have bad luck avoiding danger, might be worth the price to have this man guide you and keep your hide from harm.

According to EQ Atlas:

Paladan of the Rainkeeper of Qeynos. Sir Morgon, and his apprentice Squire Wimbley, have 
stationed themselves on the fork of the road near the giant bridge in the eastern plains. For a small 
price these two knights are willing to lend aid to lost travelers in their search for the highpass cliffs

The southern and western borders of this area are blocked by a vast river that continues flowing westward through the Northern Plains of Karana. The sole way across this is over a massive bridge in the northern part of the western edge, likely built by giants many years ago, if anything can be guessed from the massive scale of the structure.

The pass to Highpass Hold lies on the eastern edge of the zone, through a very long and narrow pass through the mountains. Note that the map is misleading, as it does not show the pass. There are two paths you can take: the low road leads to Milea Clothspinner and eventually a dead end at (-3250, -7515), while the high road takes you to the Highpass zoneline at (-3084, -8331).

One can also travel into the Gorge of King Xorbb, which lies in the northeastern corner. A trail leads past some shops on the way to the Gorge.